SOCS6 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-SOCS6 full-length
Host
Human
Theoretical MW (kDa)
59.5
Interspecies Antigen Sequence
Mouse (84); Rat (81)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-SOCS6 antibody (H00009306-D01P) by Western Blots.
SDS-PAGE Gel
SOCS6 transfected lysate.
Western Blot
Lane 1: SOCS6 transfected lysate ( 59.5 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — SOCS6
Entrez GeneID
9306GeneBank Accession#
NM_004232Protein Accession#
NP_004223.2Gene Name
SOCS6
Gene Alias
CIS4, HSPC060, SOCS4, SSI4, STAI4, STATI4
Gene Description
suppressor of cytokine signaling 6
Omim ID
605118Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene contains a SH2 domain and a CIS homolog domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by GM-CSF and EPO in hematopoietic cells. A high expression level of this gene was found in factor-independent chronic myelogenous leukemia (CML) and erythroleukemia (HEL) cell lines. [provided by RefSeq
Other Designations
STAT induced STAT inhibitor-4|cytokine-inducible SH2 protein 4|suppressor of cytokine signaling 4
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