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Last updated: 2017/6/25

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AURKB rabbit monoclonal antibody

  • Catalog # : H00009212-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human AURKB peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human AURKB is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human AURKB peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 9212
  • GeneBank Accession#:
  • AURKB
  • Gene Name:
  • AURKB
  • Gene Alias:
  • AIK2,AIM-1,AIM1,ARK2,AurB,IPL1,STK12,STK5
  • Gene Description:
  • aurora kinase B
  • Gene Summary:
  • Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases associate with microtubules during chromosome movement and segregation. Aurora kinase B localizes to microtubules near kinetochores, specifically to the specialized microtubules called K-fibers, and Aurora kinase A (MIM 603072) localizes to centrosomes (Lampson et al., 2004 [PubMed 14767480]).[supplied by OMIM
  • Other Designations:
  • aurora-1,aurora-B,serine/threonine kinase 12
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