B4GALT3 MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human B4GALT3 protein.
Immunogen
B4GALT3 (NP_003770.1, 1 a.a. ~ 393 a.a) full-length human protein.
Sequence
MLRRLLERPCTLALLVGSQLAVMMYLSLGGFRSLSALFGRDQGPTFDYSHPRDVYSNLSHLPGAPGGPPAPQGLPYCPERSPLLVGPVSVSFSPVPSLAEIVERNPRVEPGGRYRPAGCEPRSRTAIIVPHRAREHHLRLLLYHLHPFLQRQQLAYGIYVIHQAGNGTFNRAKLLNVGVREALRDEEWDCLFLHDVDLLPENDHNLYVCDPRGPRHVAVAMNKFGYSLPYPQYFGGVSALTPDQYLKMNGFPNEYWGWGGEDDDIATRVRLAGMKISRPPTSVGHYKMVKHRGDKGNEENPHRFDLLVRTQNSWTQDGMNSLTYQLLARELGPLYTNITADIGTDPRGPRAPSGPRYPPGSSQAFRQEMLQRRPPARPGPLSTANHTALRGSH
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96); Rat (96)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
B4GALT3 MaxPab rabbit polyclonal antibody. Western Blot analysis of B4GALT3 expression in human ovarian cancer.Western Blot (Transfected lysate)
Western Blot analysis of B4GALT3 expression in transfected 293T cell line (H00008703-T01) by B4GALT3 MaxPab polyclonal antibody.
Lane 1: B4GALT3 transfected lysate(43.90 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of B4GALT3 transfected lysate using anti-B4GALT3 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with B4GALT3 purified MaxPab mouse polyclonal antibody (B01P) (H00008703-B01P). -
Gene Info — B4GALT3
Entrez GeneID
8703GeneBank Accession#
NM_003779.2Protein Accession#
NP_003770.1Gene Name
B4GALT3
Gene Alias
beta4Gal-T3
Gene Description
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
Omim ID
604014Gene Ontology
HyperlinkGene Summary
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene encodes an enzyme that may be mainly involved in the synthesis of the first N-acetyllactosamine unit of poly-N-acetyllactosamine chains. [provided by RefSeq
Other Designations
OTTHUMP00000032247|OTTHUMP00000032248|UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 3|UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 3|beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase 3
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Interactome
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Pathway
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