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Last updated: 2017/10/15

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SOCS1 purified MaxPab mouse polyclonal antibody (B01P)MaxPab

  • Catalog # : H00008651-B01P
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human SOCS1 protein.
  • Immunogen:
  • SOCS1 (AAI53089.1, 1 a.a. ~ 211 a.a) full-length human protein.
  • Sequence:
  • MVAHNQVAADNAVSTAAEPRRRPEPSSSSSSSPAAPARPRPCPAVPAPAPGDTHFRTFRSHADYRRITRASALLDACGFYWGPLSVHGAHERLRAEPVGTFLVRDSRQRNCFFALSVKMASGPTSIRVHFQAGRFHLDGSRESFDCLFELLEHYVAAPRRMLGAPLRQRRVRPLQELCRQRIVATVGRENLARIPLNPVLRDYLSSFPFQI
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of SOCS1 expression in transfected 293T cell line (H00008651-T01) by SOCS1 MaxPab polyclonal antibody.

    Lane 1: SOCS1 transfected lysate(23.21 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 8651
  • Gene Name:
  • SOCS1
  • Gene Alias:
  • CIS1,CISH1,JAB,SOCS-1,SSI-1,SSI1,TIP3
  • Gene Description:
  • suppressor of cytokine signaling 1
  • Gene Summary:
  • This gene encodes a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by a subset of cytokines, including IL2, IL3 erythropoietin (EPO), CSF2/GM-CSF, and interferon (IFN)-gamma. The protein encoded by this gene functions downstream of cytokine receptors, and takes part in a negative feedback loop to attenuate cytokine signaling. Knockout studies in mice suggested the role of this gene as a modulator of IFN-gamma action, which is required for normal postnatal growth and survival. [provided by RefSeq
  • Other Designations:
  • JAK binding protein,STAT induced SH3 protein 1,Tec-interacting protein 3,cytokine-inducible SH2 protein 1
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