FKBP6 monoclonal antibody (M01), clone 8F10
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant FKBP6.
Immunogen
FKBP6 (NP_003593.2, 1 a.a. ~ 108 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MGGSALNQGVLEGDDAPGQSLYERLSQRMLDISGDRGVLKDVIREGAGDLVAPDASVLVKYYGYLEHLDRPFDSNYFRKTPRLMKLGEDITLWGMELGLLSMQRGELA
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.62 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged FKBP6 is 3 ng/ml as a capture antibody.ELISA
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Gene Info — FKBP6
Entrez GeneID
8468GeneBank Accession#
NM_003602Protein Accession#
NP_003593.2Gene Name
FKBP6
Gene Alias
FKBP36, MGC87179, PPIase
Gene Description
FK506 binding protein 6, 36kDa
Omim ID
604839Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein may have cis-trans prolyl isomerase activity, and binds to clathrin heavy chain and heat shock protein 72. This gene is found to be deleted in Williams syndrome, and the orthologous gene in mouse is essential for fertility and homologous pairing in male meiosis. [provided by RefSeq
Other Designations
FK506 binding protein 6|FK506 binding protein 6 (36kD)|FK506-binding protein 6 (36kD)|immunophilin FKBP36|peptidylprolyl cis-trans isomerase|rotamase
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Interactome
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Disease
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