BAT3 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human BAT3 peptide using ARM Technology.
Immunogen
A synthetic peptide of human BAT3 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human BAT3 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — BAT3
Entrez GeneID
7917GeneBank Accession#
BAT3Gene Name
BAT3
Gene Alias
BAG-6, BAG6, D6S52E, G3
Gene Description
HLA-B associated transcript 3
Omim ID
142590Gene Ontology
HyperlinkGene Summary
This gene was first characterized as part of a cluster of genes located within the human major histocompatibility complex class III region. This gene encodes a nuclear protein that is cleaved by caspase 3 and is implicated in the control of apoptosis. In addition, the protein forms a complex with E1A binding protein p300 and is required for the acetylation of p53 in response to DNA damage. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
HLA-B associated transcript-3|OTTHUMP00000029239|large proline-rich protein BAT3|scythe
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Interactome
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Disease
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