BSND rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human BSND peptide using ARM Technology.
Immunogen
A synthetic peptide of human BSND is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human BSND peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — BSND
Entrez GeneID
7809GeneBank Accession#
BSNDGene Name
BSND
Gene Alias
BART, MGC119283, MGC119284, MGC119285
Gene Description
Bartter syndrome, infantile, with sensorineural deafness (Barttin)
Gene Ontology
HyperlinkGene Summary
This gene encodes an essential beta subunit for CLC chloride channels. These heteromeric channels localize to basolateral membranes of renal tubules and of potassium-secreting epithelia of the inner ear. Mutations in this gene have been associated with Bartter syndrome with sensorineural deafness. [provided by RefSeq
Other Designations
OTTHUMP00000009804|barttin
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Interactome
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Disease
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