BSND monoclonal antibody (M01), clone 1E8
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant BSND.
Immunogen
BSND (NP_476517.1, 221 a.a. ~ 320 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ACSPQQEPQGCRCPLDRFQDFALIDAPTLEDEPQEGQQWEIALPNNWQRYPRTKVEEKEASDTGGEEPEKEEEDLYYGLPDGAGDLLPDKELGFEPDTQG
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (60); Rat (61)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged BSND is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — BSND
Entrez GeneID
7809GeneBank Accession#
NM_057176Protein Accession#
NP_476517.1Gene Name
BSND
Gene Alias
BART, MGC119283, MGC119284, MGC119285
Gene Description
Bartter syndrome, infantile, with sensorineural deafness (Barttin)
Gene Ontology
HyperlinkGene Summary
This gene encodes an essential beta subunit for CLC chloride channels. These heteromeric channels localize to basolateral membranes of renal tubules and of potassium-secreting epithelia of the inner ear. Mutations in this gene have been associated with Bartter syndrome with sensorineural deafness. [provided by RefSeq
Other Designations
OTTHUMP00000009804|barttin
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Interactome
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Disease
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