WHSC1 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
WHSC1 transfected lysate.
Western Blot
Lane 1: WHSC1 transfected lysate ( 71.28 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-WHSC1 full-length
Host
Human
Theoretical MW (kDa)
71.28
Interspecies Antigen Sequence
Mouse (86); Rat (85)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-WHSC1 antibody (H00007468-B01) by Western Blots.
SDS-PAGE Gel
WHSC1 transfected lysate.
Western Blot
Lane 1: WHSC1 transfected lysate ( 71.28 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — WHSC1
Entrez GeneID
7468GeneBank Accession#
NM_133334.2Protein Accession#
NP_579889.1Gene Name
WHSC1
Gene Alias
FLJ23286, KIAA1090, MGC176638, MMSET, NSD2, REIIBP, TRX5, WHS
Gene Description
Wolf-Hirschhorn syndrome candidate 1
Omim ID
602952Gene Ontology
HyperlinkGene Summary
This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences. [provided by RefSeq
Other Designations
IL5 promoter REII region-binding protein|OTTHUMP00000149955|OTTHUMP00000159146|Wolf-Hirschhorn syndrome candidate 1 protein|multiple myeloma SET domain containing protein type III|trithorax/ash1-related protein 5
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Interactome
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Pathway
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Disease
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