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WHSC1 rabbit monoclonal antibody

  • Catalog # : H00007468-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human WHSC1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human WHSC1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human WHSC1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 7468
  • GeneBank Accession#:
  • WHSC1
  • Gene Name:
  • WHSC1
  • Gene Alias:
  • FLJ23286,KIAA1090,MGC176638,MMSET,NSD2,REIIBP,TRX5,WHS
  • Gene Description:
  • Wolf-Hirschhorn syndrome candidate 1
  • Gene Summary:
  • This gene encodes a protein that contains four domains present in other developmental proteins: a PWWP domain, an HMG box, a SET domain, and a PHD-type zinc finger. It is expressed ubiquitously in early development. Wolf-Hirschhorn syndrome (WHS) is a malformation syndrome associated with a hemizygous deletion of the distal short arm of chromosome 4. This gene maps to the 165 kb WHS critical region and has also been involved in the chromosomal translocation t(4;14)(p16.3;q32.3) in multiple myelomas. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. Some transcript variants are nonsense-mediated mRNA (NMD) decay candidates, hence not represented as reference sequences. [provided by RefSeq
  • Other Designations:
  • IL5 promoter REII region-binding protein,OTTHUMP00000149955,OTTHUMP00000159146,Wolf-Hirschhorn syndrome candidate 1 protein,multiple myeloma SET domain containing protein type III,trithorax/ash1-related protein 5
  • Gene Pathway
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