UBE2D3 monoclonal antibody (M03), clone S2
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant UBE2D3.
Immunogen
UBE2D3 (AAH03395, 1 a.a. ~ 147 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MALKRINKELSDLARDPPAQCSAGPVGDDMFHWQATIMGPNDSPYQGGVFFLTIHFPTDYPFKPPKVAFTTRIYHPNINSNGSICLDILRSQWSPALTISKVLLSICSLLCDPNPDDPLVPEIARIYKTDRDKYNRISREWTQKYAM
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (100); Rat (100)
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (41.91 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — UBE2D3
Entrez GeneID
7323GeneBank Accession#
BC003395Protein Accession#
AAH03395Gene Name
UBE2D3
Gene Alias
E2(17)KB3, MGC43926, MGC5416, UBC4/5, UBCH5C
Gene Description
ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast)
Omim ID
602963Gene Ontology
HyperlinkGene Summary
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Multiple spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq
Other Designations
OTTHUMP00000161758|OTTHUMP00000161759|ubiquitin carrier protein|ubiquitin-conjugating enzyme E2-17 kDa 3|ubiquitin-conjugating enzyme E2D 3|ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC4/5)
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Interactome
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Pathway
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Disease
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