UBE2A (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human UBE2A full-length ORF ( AAH10175, 1 a.a. - 152 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MSTPARRRLMRDFKRLQEDPPAGVSGAPSENNIMVWNAVIFGPEGTPFEDGTFKLTIEFTEEYPNKPPTVRFVSKMFHPNVYADGSICLDILQNRWSPTYDVSSILTSIQSLLDEPNPNSPANSQAAQLYQENKREYEKRVSAIVEQSWRDC
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
42.46
Interspecies Antigen Sequence
Mouse (100); Rat (94)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — UBE2A
Entrez GeneID
7319GeneBank Accession#
BC010175Protein Accession#
AAH10175Gene Name
UBE2A
Gene Alias
HHR6A, RAD6A, UBC2
Gene Description
ubiquitin-conjugating enzyme E2A (RAD6 homolog)
Omim ID
312180Gene Ontology
HyperlinkGene Summary
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Multiple alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000023901|ubiquitin carrier protein A|ubiquitin-conjugating enzyme E2A|ubiquitin-protein ligase A
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Interactome
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Pathway
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