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Last updated: 2016/10/16
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TYMS MaxPab rabbit polyclonal antibody (D01)MaxPab

  • Catalog # : H00007298-D01
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against a full-length human TYMS protein.
  • Immunogen:
  • TYMS (AAH13919.1, 1 a.a. ~ 313 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • No additive
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of TYMS expression in transfected 293T cell line (H00007298-T02) by TYMS MaxPab polyclonal antibody.

    Lane 1: TYMS transfected lysate(35.70 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Immunoprecipitation
  • Immunoprecipitation
  • Immunoprecipitation of TYMS transfected lysate using anti-TYMS MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with TYMS purified MaxPab mouse polyclonal antibody (B01P) (H00007298-B01P).
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 7298
  • Gene Name:
  • TYMS
  • Gene Alias:
  • HsT422,MGC88736,TMS,TS,TSase
  • Gene Description:
  • thymidylate synthetase
  • Gene Summary:
  • Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate (methylene-THF) as a cofactor. This function maintains the dTMP (thymidine-5-prime monophosphate) pool critical for DNA replication and repair. The enzyme has been of interest as a target for cancer chemotherapeutic agents. It is considered to be the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and some folate analogs. Expression of this gene and that of a naturally occuring antisense transcript rTSalpha (GeneID:55556) vary inversely when cell-growth progresses from late-log to plateau phase. [provided by RefSeq
  • Other Designations:
  • Thymidylate synthase
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