TSG101 MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Immunoprecipitation
Immunoprecipitation of TSG101 transfected lysate using anti-TSG101 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with TSG101 purified MaxPab mouse polyclonal antibody (B01P) (H00007251-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human TSG101 protein.
Immunogen
TSG101 (ENSP00000251968, 1 a.a. ~ 390 a.a) full-length human protein.
Sequence
MAVSESQLKKMVSKYKYRDLTVRETVNVITLYKDLKPVLDSYVFNDGSSRELMNLTGTIPVPYRGNTYNIPICLWLLDTYPYNPPICFVKPTSSMTIKTGKHVDANGKIYLPYLHEWKHPQSDLLGLIQVMIVVFGDEPPVFSRPISASYPPYQATGPPNTSYMPGMPGGISPYPSGYPPNPSGYPGCPYPPGGPYPATTSSQYPSQPPVTTVGPSRDGTISEDTIRASLISAVSDKLRWRMKEEMDRAQAELNALKRTEEDLKKGHQKLEEMVTRLDQEVAEVDKNIELLKKKDEELSSALEKMENQSENNDIDEVIIPTAPLYKQILNLYAEENAIEDTIFYLGEALRRGVIDLDVFLKHVRLLSRKQFQLRALMQKARKTAGLSDLY
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Immunoprecipitation
Immunoprecipitation of TSG101 transfected lysate using anti-TSG101 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with TSG101 purified MaxPab mouse polyclonal antibody (B01P) (H00007251-B01P). -
Gene Info — TSG101
Entrez GeneID
7251GeneBank Accession#
NM_006292.2Protein Accession#
ENSP00000251968Gene Name
TSG101
Gene Alias
TSG10, VPS23
Gene Description
tumor susceptibility gene 101
Omim ID
601387Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq
Other Designations
tumor susceptibility protein
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Interactome
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Pathway
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Disease
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