TSG101 recombinant monoclonal antibody, clone R01-4D9
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More Files
- More Functions
Western Blot
Western blot analysis of Lane1: K562, Lane2: rat brain, Lane3: C6, Lane4: 3T3 and Lane5: Hela lysates with TSG101 recombinant monoclonal antibody, clone R01-4D9 (Cat # RAB01850).
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human TSG101.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human TSG101.
Theoretical MW (kDa)
Calculated MW: 44 kD
Reactivity
Human, Mouse, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Immunofluorescence (1:50-1:200)
Immunohistochemistry (1:50-1:100)
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
Western blot analysis of Lane1: K562, Lane2: rat brain, Lane3: C6, Lane4: 3T3 and Lane5: Hela lysates with TSG101 recombinant monoclonal antibody, clone R01-4D9 (Cat # RAB01850).Immunohistochemistry
Immunofluorescence
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Gene Info — TSG101
Entrez GeneID
7251Protein Accession#
Q99816Gene Name
TSG101
Gene Alias
TSG10, VPS23
Gene Description
tumor susceptibility gene 101
Omim ID
601387Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression. [provided by RefSeq
Other Designations
tumor susceptibility protein
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Interactome
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Pathway
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Disease
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