CLDN5 monoclonal antibody (M01), clone 3D8
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Specifications
Product Description
Mouse monoclonal antibody raised against a partial recombinant CLDN5.
Immunogen
CLDN5 (NP_003268, 29 a.a. ~ 81 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MWQVTAFLDHNIVTAQTTWKGLWMSCVVQSTGHMQCKVYDSVLALSTEVQAAR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96); Rat (96)
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged CLDN5 is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — CLDN5
Entrez GeneID
7122GeneBank Accession#
NM_003277Protein Accession#
NP_003268Gene Name
CLDN5
Gene Alias
AWAL, BEC1, CPETRL1, TMVCF
Gene Description
claudin 5
Omim ID
602101Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
androgen withdrawal and apoptosis induced protein RVP1-like|transmembrane protein deleted in velocardiofacial syndrome
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Interactomes
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Pathways
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Diseases
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