CLDN5 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of CLDN5.
Immunogen
A synthetic peptide corresponding to human CLDN5.
Host
Rabbit
Theoretical MW (kDa)
23
Reactivity
Human, Mouse, Rat
Specificity
CLDN5 polyclonal antibody detects endogenous levels of CLDN5 protein.
Form
Liquid
Purification
Antigen affinity purification
Concentration
1 mg/mL
Recommend Usage
Western Blot (1:500-1:1000)
Immunohistochemistry (1:50-1:200)
Immunofluorescence (1:50-1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.2 (0.05% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of CLDN5 polyclonal antibody (Cat # PAB27037) in extracts from A-549 cells.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemical analysis of CLDN5 polyclonal antibody (Cat # PAB27037) in paraffin-embedded human brain tissue.Enzyme-linked Immunoabsorbent Assay
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Gene Info — CLDN5
Entrez GeneID
7122Protein Accession#
O00501Gene Name
CLDN5
Gene Alias
AWAL, BEC1, CPETRL1, TMVCF
Gene Description
claudin 5
Omim ID
602101Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets. Mutations in this gene have been found in patients with velocardiofacial syndrome. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq
Other Designations
androgen withdrawal and apoptosis induced protein RVP1-like|transmembrane protein deleted in velocardiofacial syndrome
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Interactome
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Pathway
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Disease
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