TGFBR2 polyclonal antibody (A01)
* The price is valid only in USA. Please select country.
-
More Files
- More Functions
-
Specifications
Product Description
Mouse polyclonal antibody raised against a partial recombinant TGFBR2.
Immunogen
TGFBR2 (NP_001020018, 62 a.a. ~ 165 a.a) partial recombinant protein with GST tag.
Sequence
IVTDNNGAVKFPQLCKFCDVRFSTCDNQKSCMSNCSITSICEKPQEVCVAVWRKNDENITLETVCHDPKLPYHDFILEDAASPKCIMKEKKKPGETFFMCSCSS
Host
Mouse
Reactivity
Human, Mouse
Interspecies Antigen Sequence
Mouse (83)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (37.55 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
-
Applications
Western Blot (Cell lysate)
TGFBR2 polyclonal antibody (A01), Lot # 060525JCSI. Western Blot analysis of TGFBR2 expression in Raw 264.7.Western Blot (Recombinant protein)
ELISA
-
Gene Info — TGFBR2
Entrez GeneID
7048GeneBank Accession#
NM_001024847Protein Accession#
NP_001020018Gene Name
TGFBR2
Gene Alias
AAT3, FAA3, LDS1B, LDS2B, MFS2, RIIC, TAAD2, TGFR-2, TGFbeta-RII
Gene Description
transforming growth factor, beta receptor II (70/80kDa)
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized. [provided by RefSeq
Other Designations
TGF-beta receptor type IIB|TGF-beta type II receptor|transforming growth factor beta receptor type IIC|transforming growth factor, beta receptor II|transforming growth factor, beta receptor II (70-80kD)
-
Interactomes
-
Pathways
-
Diseases
-
Publication Reference
-
Halofuginone enhances the radiation sensitivity of human tumor cell lines.
Cook JA, Choudhuri R, Degraff W, Gamson J, Mitchell JB.
Cancer Letters 2010 Mar; 289(1):119.
Application:WB-Ce, Human, DU-145, HT-29, MCF-7, PC-Sw, SNU-638 cells.
-
Halofuginone enhances the radiation sensitivity of human tumor cell lines.
- +1-909-264-1399
+1-909-992-0619
Toll Free : +1-877-853-6098 - +1-909-992-3401
- sales@abnova.com