TFF1 (Human) Recombinant Protein (P01)
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More Files
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Specifications
Product Description
Human TFF1 full-length ORF ( AAH32811.1, 1 a.a. - 84 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MATMENKVICALVLVSMLALGTLAEAQTETCTVAPRERQNCGFPGVTPSQCANKGCCFDDTVRGVPWCFYPNTIDVPPEEECEF
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
34.98
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — TFF1
Entrez GeneID
7031GeneBank Accession#
BC032811Protein Accession#
AAH32811.1Gene Name
TFF1
Gene Alias
BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2
Gene Description
trefoil factor 1
Omim ID
113710Gene Ontology
HyperlinkGene Summary
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq
Other Designations
breast cancer estrogen-inducible sequence|gastrointestinal trefoil protein pS2
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Interactomes
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Diseases
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Publication Reference
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Pathophysiological Investigation of the Gastric Surface Mucous Gel Layer of Patients with Helicobacter pylori Infection by Using Immunoassays for Trefoil Factor Family 2 and Gastric Gland Mucous Cell-Type Mucin in Gastric Juice.
Kubota S, Yamauchi K, Sugano M, Kawasaki K, Sugiyama A, Matsuzawa K, Akamatsu T, Ohmoto Y, Ota H.
Digestive Diseases and Sciences 2011 Dec; 56(12):3498.
Application:ELISA, Human, Gastric juice.
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The aurora kinase A regulates GSK-3?] in gastric cancer cells.
Dar AA, Belkhiri A, El-Rifai W.
Oncogene 2009 Feb; 28(6):866.
Application:KA, Recombinant protein.
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Pathophysiological Investigation of the Gastric Surface Mucous Gel Layer of Patients with Helicobacter pylori Infection by Using Immunoassays for Trefoil Factor Family 2 and Gastric Gland Mucous Cell-Type Mucin in Gastric Juice.
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