TFF1 (Human) Recombinant Protein
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Specification
Product Description
Human TFF1 (P04155) recombinant protein expressed in E. Coli.
Sequence
EAQTETCTVAPRERQNCGFPGVTPSQCANKGCCFDDTVRGVPWCFYPNTIDVPPEEECEF
Host
Escherichia coli
Theoretical MW (kDa)
7
Form
Lyophilized
Purity
> 95%
Endotoxin Level
<= 1 EUs/ug (LAL gel clot method)
Activity
Determined by the ability to chemoattract human MCF-7 cells using a concentration 5-10 ug/mL.
Storage Buffer
Lyophilized from PBS, pH 7.2.
Storage Instruction
Stored at -20°C to-80°C.
After reconstitution with sterile water not less than 0.1 mg/mL, store at -20°C to -80°C for 6 months, store at 4°C for 1 month.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Functional Study
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Gene Info — TFF1
Entrez GeneID
7031Protein Accession#
P04155Gene Name
TFF1
Gene Alias
BCEI, D21S21, HP1.A, HPS2, pNR-2, pS2
Gene Description
trefoil factor 1
Omim ID
113710Gene Ontology
HyperlinkGene Summary
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq
Other Designations
breast cancer estrogen-inducible sequence|gastrointestinal trefoil protein pS2
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