Western blot analysis of TFAP2A over-expressed 293 cell line, cotransfected with TFAP2A Validated Chimera RNAi ( Cat # H00007020-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with TFAP2A monoclonal antibody (M01), clone 2G5 (Cat # H00007020-M01 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.
AP2-alpha is a 52-kD retinoic acid-inducible and developmentally regulated activator of transcription that binds to a consensus DNA-binding sequence CCCCAGGC in the SV40 and metallothionein (MIM 156350) promoters.[supplied by OMIM
OTTHUMP00000016013,OTTHUMP00000016014,activating enhancer-binding protein 2 alpha,transcription factor AP-2 alpha,transcription factor AP-2 alpha (activating enhancer-binding protein 2 alpha)