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Last updated: 2016/10/23
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TDG purified MaxPab mouse polyclonal antibody (B01P)MaxPab

  • Catalog # : H00006996-B01P
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a full-length human TDG protein.
  • Immunogen:
  • TDG (AAH37557.1, 1 a.a. ~ 410 a.a) full-length human protein.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of TDG expression in transfected 293T cell line (H00006996-T01) by TDG MaxPab polyclonal antibody.

    Lane 1: TDG transfected lysate(45.1 KDa).
    Lane 2: Non-transfected lysate.
  • PDF DownloadProtocol Download
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 6996
  • Gene Name:
  • TDG
  • Gene Alias:
  • -
  • Gene Description:
  • thymine-DNA glycosylase
  • Gene Summary:
  • The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. [provided by RefSeq
  • Other Designations:
  • G/T mismatch-specific thymine DNA glycosylase
  • Gene Pathway
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