SSX1 monoclonal antibody (M01), clone 5B2
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More Files
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Specifications
Product Description
Mouse monoclonal antibody raised against a partial recombinant SSX1.
Immunogen
SSX1 (NP_005626.1, 89 a.a. ~ 188 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
NRRIQVEHPQMTFGRLHRIIPKIMPKKPAEDENDSKGVSEASGPQNDGKQLHPPGKANISEKINKRSGPKRGKHAWTHRLRERKQLVIYEEISDPEEDDE
Host
Mouse
Reactivity
Human
Isotype
IgG2b Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of SSX1 expression in transfected 293T cell line by SSX1 monoclonal antibody (M01), clone 5B2.
Lane 1: SSX1 transfected lysate (Predicted MW: 21.9 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SSX1 is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — SSX1
Entrez GeneID
6756GeneBank Accession#
NM_005635.2Protein Accession#
NP_005626.1Gene Name
SSX1
Gene Alias
MGC150425, MGC5162, SSRC
Gene Description
synovial sarcoma, X breakpoint 1
Omim ID
312820Gene Ontology
HyperlinkGene Summary
The product of this gene belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X;18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. [provided by RefSeq
Other Designations
OTTHUMP00000023245|sarcoma, synovial, X-chromosome-related 1
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Interactomes
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