SFTPB monoclonal antibody (M02), clone 2H6
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of SFTPB expression in transfected 293T cell line by SFTPB monoclonal antibody (M02), clone 2H6.
Lane 1: SFTPB transfected lysate (Predicted MW: 42.1 KDa).
Lane 2: Non-transfected lysate.
Western Blot detection against Immunogen (68.5 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant SFTPB.
Immunogen
SFTPB (NP_000533.2, 1 a.a. ~ 381 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MAESHLLQWLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVWGHVGADDLCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPLPDPLLDKLVLPVLPGALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGALAVAVAQVCRVVPLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPRSPTGEWLPRDSECHLCMSVTTQAGNSSEQAIPQAMLQACVGSWLDREKCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVCGTMSSPLQCIHSPDL
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (68.5 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of SFTPB expression in transfected 293T cell line by SFTPB monoclonal antibody (M02), clone 2H6.
Lane 1: SFTPB transfected lysate (Predicted MW: 42.1 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
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Gene Info — SFTPB
Entrez GeneID
6439GeneBank Accession#
NM_000542.2Protein Accession#
NP_000533.2Gene Name
SFTPB
Gene Alias
PSP-B, SFTB3, SFTP3, SMDP1, SP-B
Gene Description
surfactant protein B
Gene Ontology
HyperlinkGene Summary
The SFTPB gene encodes the pulmonary-associated surfactant B protein (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a lipid-rich material that prevents lung collapse by lowering surface tension at the air-liquid interface in the alveoli of lung. SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Surfactant is composed of phospholipids and other surfactant-associated proteins (Clark et al., 1995 [PubMed 7644495]). See also SFTPA1 (MIM 178630), SFTPC (MIM 178620), and SFTPD (MIM 178635).[supplied by OMIM
Other Designations
Pulmonary surfactant-associated protein B, 18kD|surfactant, pulmonary-associated protein B
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Disease
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