SFTPB monoclonal antibody (M01), clone 1H7
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More Files
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Western Blot (Tissue lysate)
SFTPB monoclonal antibody (M01), clone 1H7. Western Blot analysis of SFTPB expression in human lung cancer.
Western Blot (Transfected lysate)
Western Blot analysis of SFTPB expression in transfected 293T cell line by SFTPB monoclonal antibody (M01), clone 1H7.
Lane 1: SFTPB transfected lysate (Predicted MW: 42.1 KDa).
Lane 2: Non-transfected lysate.
Western Blot detection against Immunogen (68.5 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant SFTPB.
Immunogen
SFTPB (NP_000533.2, 1 a.a. ~ 381 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MAESHLLQWLLLLLPTLCGPGTAAWTTSSLACAQGPEFWCQSLEQALQCRALGHCLQEVWGHVGADDLCQECEDIVHILNKMAKEAIFQDTMRKFLEQECNVLPLKLLMPQCNQVLDDYFPLVIDYFQNQTDSNGICMHLGLCKSRQPEPEQEPGMSDPLPKPLRDPLPDPLLDKLVLPVLPGALQARPGPHTQDLSEQQFPIPLPYCWLCRALIKRIQAMIPKGALAVAVAQVCRVVPLVAGGICQCLAERYSVILLDTLLGRMLPQLVCRLVLRCSMDDSAGPRSPTGEWLPRDSECHLCMSVTTQAGNSSEQAIPQAMLQACVGSWLDREKCKQFVEQHTPQLLTLVPRGWDAHTTCQALGVCGTMSSPLQCIHSPDL
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (68.5 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
SFTPB monoclonal antibody (M01), clone 1H7. Western Blot analysis of SFTPB expression in human lung cancer.Western Blot (Transfected lysate)
Western Blot analysis of SFTPB expression in transfected 293T cell line by SFTPB monoclonal antibody (M01), clone 1H7.
Lane 1: SFTPB transfected lysate (Predicted MW: 42.1 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
ELISA
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Gene Info — SFTPB
Entrez GeneID
6439GeneBank Accession#
NM_000542.2Protein Accession#
NP_000533.2Gene Name
SFTPB
Gene Alias
PSP-B, SFTB3, SFTP3, SMDP1, SP-B
Gene Description
surfactant protein B
Gene Ontology
HyperlinkGene Summary
The SFTPB gene encodes the pulmonary-associated surfactant B protein (SPB), an amphipathic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a lipid-rich material that prevents lung collapse by lowering surface tension at the air-liquid interface in the alveoli of lung. SPB enhances the rate of spreading and increases the stability of surfactant monolayers in vitro. Surfactant is composed of phospholipids and other surfactant-associated proteins (Clark et al., 1995 [PubMed 7644495]). See also SFTPA1 (MIM 178630), SFTPC (MIM 178620), and SFTPD (MIM 178635).[supplied by OMIM
Other Designations
Pulmonary surfactant-associated protein B, 18kD|surfactant, pulmonary-associated protein B
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Disease
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