CCL23 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human CCL23 full-length ORF ( NP_005055.2, 1 a.a. - 137 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MKVSVAALSCLMLVTALGSQARVTKDAETEFMMSKLPLENPVLLDMLWRRKIGPQMTLSHAAGFHATSADCCISYTPRSIPCSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQVCVRMLKLDTRIKTRKN
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
41.7
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CCL23
Entrez GeneID
6368GeneBank Accession#
NM_005064.3Protein Accession#
NP_005055.2Gene Name
CCL23
Gene Alias
CK-BETA-8, CKb8, Ckb-8, Ckb-8-1, MIP-3, MIP3, MPIF-1, SCYA23
Gene Description
chemokine (C-C motif) ligand 23
Omim ID
602494Gene Ontology
HyperlinkGene Summary
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist at CC chemokine receptor 1. Two alternatively spliced variants encoding different active isoforms have been identified. [provided by RefSeq
Other Designations
C6 beta-chemokine|OTTHUMP00000163948|hmrp-2a|macrophage inflammatory protein 3|myeloid progenitor inhibitory factor 1|small inducible cytokine A23|small inducible cytokine subfamily A (Cys-Cys), member 23
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