CCL23 (Human) Recombinant Protein
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Specification
Product Description
Human CCL23 (P55773, 22 a.a. - 123 a.a.) partial recombinant protein expressed in Escherichia coli.
Sequence
RVTKDAETEFMMSKLPLENPVLLDRFHATSADCCISYTPRSIPCSLLESYFETNSECSKPGVIFLTKKGRRFCANPSDKQVQVCMRMLKLDTRIKTRKN
Host
Escherichia coli
Theoretical MW (kDa)
11.3
Form
Lyophilized
Preparation Method
Escherichia coli expression system
Purity
> 97.0% by SDS-PAGE
Activity
The Biological activity is 10 - 50 ng/mL, was determined by the ability to chemoattract human T cell population, corresponding to a specific activity of 20000 - 100000 IU/mg.
Recommend Usage
Biological Activity
SDS-PAGE
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from sterile distilled Water is > 100 ug/mL
Storage Instruction
Store at 2°C to 8°C for 1 week. For long term storage, aliquot and store at -20°C to -80°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Functional Study
SDS-PAGE
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Gene Info — CCL23
Entrez GeneID
6368Protein Accession#
P55773Gene Name
CCL23
Gene Alias
CK-BETA-8, CKb8, Ckb-8, Ckb-8-1, MIP-3, MIP3, MPIF-1, SCYA23
Gene Description
chemokine (C-C motif) ligand 23
Omim ID
602494Gene Ontology
HyperlinkGene Summary
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene displays chemotactic activity on resting T lymphocytes and monocytes, lower activity on neutrophils and no activity on activated T lymphocytes. The protein is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. In addition, the product of this gene is a potent agonist at CC chemokine receptor 1. Two alternatively spliced variants encoding different active isoforms have been identified. [provided by RefSeq
Other Designations
C6 beta-chemokine|OTTHUMP00000163948|hmrp-2a|macrophage inflammatory protein 3|myeloid progenitor inhibitory factor 1|small inducible cytokine A23|small inducible cytokine subfamily A (Cys-Cys), member 23
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