RGS1 purified MaxPab mouse polyclonal antibody (B02P)
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More Files
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Specifications
Product Description
Mouse polyclonal antibody raised against a full-length human RGS1 protein.
Immunogen
RGS1 (AAH15510.1, 1 a.a. ~ 196 a.a) full-length human protein.
Sequence
MPGMFFSANPKELKGTTHSLLDDKMQKRRPKTFGMDMKAYLRSMIPHLESGMKSSKSKDVLSAAEVMQWSQSLEKLLANQTGQNVFGSFLKSEFSEENIEFWLACEDYKKTESDLLPCKAEEIYKAFVHSDAAKQINIDFRTRESTAKKIKAPTPTCFDEAQKVIYTLMEKDSYPRFLKSDIYLNLLNDLQANSLK
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of RGS1 expression in transfected 293T cell line (H00005996-T02) by RGS1 MaxPab polyclonal antibody.
Lane 1: RGS1 transfected lysate(21.56 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — RGS1
Entrez GeneID
5996GeneBank Accession#
NM_002922Protein Accession#
AAH15510.1Gene Name
RGS1
Gene Alias
1R20, BL34, IER1, IR20
Gene Description
regulator of G-protein signaling 1
Omim ID
600323Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the regulator of G-protein signalling family. This protein is located on the cytosolic side of the plasma membrane and contains a conserved, 120 amino acid motif called the RGS domain. The protein attenuates the signalling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. [provided by RefSeq
Other Designations
B-cell activation protein BL34|OTTHUMP00000033591|early response protein 1R20|immediate-early response 1, B-cell specific|regulator of G-protein signalling 1
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Diseases
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