PVRL2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human PVRL2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human PVRL2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human PVRL2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — PVRL2
Entrez GeneID
5819GeneBank Accession#
PVRL2Gene Name
PVRL2
Gene Alias
CD112, HVEB, PRR2, PVRR2
Gene Description
poliovirus receptor-related 2 (herpesvirus entry mediator B)
Omim ID
600798Gene Ontology
HyperlinkGene Summary
This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
herpesvirus entry mediator B|herpesvirus entry protein B|nectin 2|poliovirus receptor related 2|poliovirus receptor-like 2
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