PVRL2 monoclonal antibody (M01), clone 2A6-2C1
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More Files
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Western Blot (Transfected lysate)
Western Blot analysis of PVRL2 expression in transfected 293T cell line by PVRL2 monoclonal antibody (M01), clone 2A6-2C1.
Lane 1: PVRL2 transfected lysate (Predicted MW: 51.4 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of PVRL2 transfected lysate using anti-PVRL2 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with PVRL2 MaxPab rabbit polyclonal antibody.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PVRL2 is 1 ng/ml as a capture antibody.
Western Blot detection against Immunogen (78.43 KDa) .
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant PVRL2.
Immunogen
PVRL2 (AAH03091, 1 a.a. ~ 479 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MARAAALLPSRSPPTPLLWPLLLLLFLETGAQDVRVQVLPEVRGQLGGTVELPCHLLPPVPGLYISLVTWQRPDAPANHQNVAAFHPKMGPSFPSPKPGSERLSFVSAKQSTGQDTEAELQDATLALHGLTVEDEGNYTCEFATFPKGSVRGMTWLRVIAKPKNQAEAQKVTFSQDPTTVALCISKEGRPPARISWLSSLDWEAKETQVSGTLAGTVTVTSRFTLVPSGRADGVTVTCKVEHESFEEPALIPVTLSVRYPPEVSISGYDDNWYLGRTDATLSCDVRSNPEPTGYDWSTTSGTFPTSAVAQGSQLVIHAVDSLFNTTFVCTVTNAVGMGRAEQVIFVRETPRASPRDVGPLVWGAVGGTLLVLLLLAGGSLAFILLRVRRRRKSPGGAGGGASGDGGFYDPKAQVLGNGDPVFWTPVVPGPMEPDGKDEEEEEEEEKAEKGLMLPPPPALEDDMESQLDGSLISRRAVYV
Host
Mouse
Reactivity
Human
Isotype
IgG2a kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (78.43 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of PVRL2 expression in transfected 293T cell line by PVRL2 monoclonal antibody (M01), clone 2A6-2C1.
Lane 1: PVRL2 transfected lysate (Predicted MW: 51.4 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Immunoprecipitation
Immunoprecipitation of PVRL2 transfected lysate using anti-PVRL2 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with PVRL2 MaxPab rabbit polyclonal antibody.Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged PVRL2 is 1 ng/ml as a capture antibody.ELISA
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Gene Info — PVRL2
Entrez GeneID
5819GeneBank Accession#
BC003091Protein Accession#
AAH03091Gene Name
PVRL2
Gene Alias
CD112, HVEB, PRR2, PVRR2
Gene Description
poliovirus receptor-related 2 (herpesvirus entry mediator B)
Omim ID
600798Gene Ontology
HyperlinkGene Summary
This gene encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. This protein is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
Other Designations
herpesvirus entry mediator B|herpesvirus entry protein B|nectin 2|poliovirus receptor related 2|poliovirus receptor-like 2
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Interactome
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Pathway
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Disease
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