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Last updated: 2016/10/23

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PRELP monoclonal antibody (M01A), clone 3H1

  • Catalog # : H00005549-M01A
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against a partial recombinant PRELP.
  • Immunogen:
  • PRELP (NP_002716.1, 281 a.a. ~ 365 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
  • Sequence:
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Isotype:
  • IgM Kappa
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.

    QC Testing of H00005549-M01A
    Western Blot detection against Immunogen (35.09 KDa) .
  • Storage Buffer:
  • In ascites fluid
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Application Image
  • Western Blot (Recombinant protein)
  • Gene Information
  • Entrez GeneID:
  • 5549
  • Gene Name:
  • Gene Alias:
  • MGC45323,MST161,MSTP161,SLRR2A
  • Gene Description:
  • proline/arginine-rich end leucine-rich repeat protein
  • Gene Summary:
  • The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed. [provided by RefSeq
  • Other Designations:
  • 55 kDa leucine-rich repeat protein of articular cartilage,OTTHUMP00000034099,prolargin proteoglycan,proline arginine-rich end leucine-rich repeat protein
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