PMS1 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human PMS1 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MKQLPAATVRLLSSSQIITSVVSVVKELIENSLDAGATSVDVKLENYGFDKIEVRDNGEGIKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQYVLDGSGHILSQKPSHLGQGKKVALYTNILYLFCLNCWFKKKKVTR
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — PMS1
Entrez GeneID
5378GeneBank Accession#
BC008410Protein Accession#
AAH08410Gene Name
PMS1
Gene Alias
DKFZp781M0253, FLJ98259, HNPCC3, PMSL1, hPMS1
Gene Description
PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
Omim ID
600258Gene Ontology
HyperlinkGene Summary
This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq
Other Designations
human homolog of yeast mutL|mismatch repair gene PMSL1|postmeiotic segregation 1|rhabdomyosarcoma antigen MU-RMS-40.10B|rhabdomyosarcoma antigen MU-RMS-40.10E
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Interactome
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Disease
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