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Last updated: 2017/4/30

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PMS1 rabbit monoclonal antibody

  • Catalog # : H00005378-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human PMS1 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human PMS1 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human PMS1 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 5378
  • GeneBank Accession#:
  • PMS1
  • Gene Name:
  • PMS1
  • Gene Alias:
  • DKFZp781M0253,FLJ98259,HNPCC3,PMSL1,hPMS1
  • Gene Description:
  • PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
  • Gene Summary:
  • This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq
  • Other Designations:
  • human homolog of yeast mutL,mismatch repair gene PMSL1,postmeiotic segregation 1,rhabdomyosarcoma antigen MU-RMS-40.10B,rhabdomyosarcoma antigen MU-RMS-40.10E
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