PMS1 polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant PMS1.
Immunogen
PMS1 (NP_000525, 26 a.a. ~ 135 a.a) partial recombinant protein with GST tag.
Sequence
KELIENSLDAGATSVDVKLENYGFDKIEVRDNGEGIKAVDAPVMAMKYYTSKINSHEDLENLTTYGFRGEALGSICCIAEVLITTRTAADNFSTQYVLDGSGHILSQKPS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (88); Rat (86)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (38.21 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — PMS1
Entrez GeneID
5378GeneBank Accession#
NM_000534Protein Accession#
NP_000525Gene Name
PMS1
Gene Alias
DKFZp781M0253, FLJ98259, HNPCC3, PMSL1, hPMS1
Gene Description
PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
Omim ID
600258Gene Ontology
HyperlinkGene Summary
This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq
Other Designations
human homolog of yeast mutL|mismatch repair gene PMSL1|postmeiotic segregation 1|rhabdomyosarcoma antigen MU-RMS-40.10B|rhabdomyosarcoma antigen MU-RMS-40.10E
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Interactome
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Disease
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