PFKFB1 purified MaxPab rabbit polyclonal antibody (D01P)
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Specifications
Product Description
Rabbit polyclonal antibody raised against a full-length human PFKFB1 protein.
Immunogen
PFKFB1 (NP_002616.1, 1 a.a. ~ 471 a.a) full-length human protein.
Sequence
MSPEMGELTQTRLQKIWIPHSSGSSRLQRRRGSSIPQFTNSPTMVIMVGLPARGKTYISTKLTRYLNWIGTPTKVFNLGQYRREAVSYKNYEFFLPDNMEALQIRKQCALAALKDVHNYLSHEEGHVAVFDATNTTRERRSLILQFAKEHGYKVFFIESICNDPGIIAENIRQVKLGSPDYIDCDREKVLEDFLKRIECYEVNYQPLDEELDSHLSYIKIFDVGTRYMVNRVQDHIQSRTVYYLMNIHVTPRSIYLCRHGESELNIRGRIGGDSGLSVRGKQYAYALANFIQSQGISSLKVWTSRMKRTIQTAEALGVPYEQWKALNEIDAGVCEEMTYEEIQEHYPEEFALRDQDKYRYRYPKGESYEDLVQRLEPVIMELERQENVLVICHQAVMRCLLAYFLDKSSDELPYLKCPLHTVLKLTPVAYGCKVESIYLNVEAVNTHREKPENVDITREPEEALDTVPAHY
Host
Rabbit
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of PFKFB1 expression in transfected 293T cell line (H00005207-T01) by PFKFB1 MaxPab polyclonal antibody.
Lane 1: PFKFB1 transfected lysate(54.70 KDa).
Lane 2: Non-transfected lysate.
Immunofluorescence
Immunofluorescence of purified MaxPab antibody to PFKFB1 on HeLa cell. [antibody concentration 20 ug/ml] -
Gene Info — PFKFB1
Entrez GeneID
5207GeneBank Accession#
NM_002625.1Protein Accession#
NP_002616.1Gene Name
PFKFB1
Gene Alias
F6PK, HL2K, MGC116715, MGC116717, PFRX
Gene Description
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Omim ID
311790Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. [provided by RefSeq
Other Designations
6PF-2-K/Fru-2,6-P2ASE liver isozyme|OTTHUMP00000023391|fructose-2,6-bisphosphatase|fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase
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Interactomes
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Pathways
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Diseases
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