MRC1 polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (38.1 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant MRC1.
Immunogen
MRC1 (NP_002429, 22 a.a. ~ 130 a.a) partial recombinant protein with GST tag.
Sequence
TRQFLIYNEDHKRCVDAVSPSAVQTAACNQDAESQKFRWVSESQIMSVAFKLCLGVPSKTDWVAITLYACDSKSEFQKWECKNDTLLGIKGEDLFFNYGNRQEKNIMLY
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (84); Rat (85)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (38.1 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — MRC1
Entrez GeneID
4360GeneBank Accession#
NM_002438Protein Accession#
NP_002429Gene Name
MRC1
Gene Alias
CD206, CLEC13D, MMR
Gene Description
mannose receptor, C type 1
Omim ID
153618Gene Ontology
HyperlinkGene Summary
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. This gene is in close proximity to MRC1L1. The gene loci including this gene, MRC1L1, as well as LOC340843 and LOC340893, consist of two nearly identical, tandemly linked genomic regions, which are thought to be a part of a duplicated region. [provided by RefSeq
Other Designations
OTTHUMP00000019245|OTTHUMP00000045206|macrophage mannose receptor|mannose receptor C type 1
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Interactome
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Disease
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