MRC1 recombinant monoclonal antibody, clone R06-5I1
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Specification
Product Description
Rabbit recombinant monoclonal antibody raised against human MRC1.
Antibody Species
Rabbit
Immunogen
Original antibody is raised against a synthetic peptide corresponding to human MRC1.
Theoretical MW (kDa)
Calculated MW: 166 k
Reactivity
Human, Rat
Form
Liquid
Purification
Affinity purification
Isotype
IgG
Recommend Usage
Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In 50 mM Tris-Glycine, pH 7.4 (0.15 M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA)
Storage Instruction
Store at -20 °C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot
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Gene Info — MRC1
Entrez GeneID
4360Protein Accession#
P22897Gene Name
MRC1
Gene Alias
CD206, CLEC13D, MMR
Gene Description
mannose receptor, C type 1
Omim ID
153618Gene Ontology
HyperlinkGene Summary
The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment. This gene is in close proximity to MRC1L1. The gene loci including this gene, MRC1L1, as well as LOC340843 and LOC340893, consist of two nearly identical, tandemly linked genomic regions, which are thought to be a part of a duplicated region. [provided by RefSeq
Other Designations
OTTHUMP00000019245|OTTHUMP00000045206|macrophage mannose receptor|mannose receptor C type 1
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