ALDH6A1 MaxPab mouse polyclonal antibody (B01)
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human ALDH6A1 protein.
Immunogen
ALDH6A1 (NP_005580.1, 1 a.a. ~ 535 a.a) full-length human protein.
Sequence
MAALLAAAAVRARILQVSSKVKSSPTWYSASSFSSSVPTVKLFIGGKFVESKSDKWIDIHNPATNEVIGRVPQATKAEMDAAIASCKRAFPAWADTSVLSRQQVLLRYQQLIKENLKEIAKLITLEQGKTLADAEGDVFRGLQVVEHACSVTSLMMGETMPSITKDMDLYSYRLPLGVCAGIAPFNFPAMIPLWMFPMAMVCGNTFLMKPSERVPGATMLLAKLLQDSGAPDGTLNIIHGQHEAVNFICDHPDIKAISFVGSNKAGEYIFERGSRHGKRVQANMGAKNHGVVMPDANKENTLNQLVGAAFGAAGQRCMALSTAVLVGEAKKWLPELVEHAKNLRVNAGDQPGADLGPLITPQAKERVCNLIDSGTKEGASILLDGRKIKVKGYENGNFVGPTIISNVKPNMTCYKEEIFGPVLVVLETETLDEAIQIVNNNPYGNGTAIFTTNGATARKYAHLVDVGQVGVNVPIPVPLPMFSFTGSRSSFRGDTNFYGKQGIQFYTQLKTITSQWKEEDATLSSPAVVMPTMGR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Note
For IHC and IF applications, antibody purification with Protein A will be needed prior to use.
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Applications
Western Blot (Tissue lysate)
ALDH6A1 MaxPab polyclonal antibody. Western Blot analysis of ALDH6A1 expression in human liver.Western Blot (Transfected lysate)
Western Blot analysis of ALDH6A1 expression in transfected 293T cell line (H00004329-T01) by ALDH6A1 MaxPab polyclonal antibody.
Lane 1: ALDH6A1 transfected lysate(58.85 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — ALDH6A1
Entrez GeneID
4329GeneBank Accession#
NM_005589.2Protein Accession#
NP_005580.1Gene Name
ALDH6A1
Gene Alias
MGC40271, MMSADHA, MMSDH
Gene Description
aldehyde dehydrogenase 6 family, member A1
Omim ID
603178Gene Ontology
HyperlinkGene Summary
This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. [provided by RefSeq
Other Designations
aldehyde dehydrogenase 6A1|mitochondrial acylating methylmalonate-semialdehyde dehydrogenase
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Interactome
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Pathway
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Disease
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Publication Reference
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Network Clustering Revealed the Systemic Alterations of Mitochondrial Protein Expression.
Jeon J, Jeong JH, Baek JH, Koo HJ, Park WH, Yang JS, Yu MH, Kim S, Pak YK.
PLoS Computational Biology 2011 Jun; 7(6):e1002093.
Application:WB-Ce, Human, 143B TK- osteosarcoma cells.
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Network Clustering Revealed the Systemic Alterations of Mitochondrial Protein Expression.
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