ALDH6A1 293T Cell Transient Overexpression Lysate(Denatured)
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-ALDH6A1 full-length
Host
Human
Theoretical MW (kDa)
58.96
Interspecies Antigen Sequence
Mouse (95); Rat (95)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-ALDH6A1 antibody (H00004329-B01) by Western Blots.
SDS-PAGE Gel
ALDH6A1 transfected lysate.
Western Blot
Lane 1: ALDH6A1 transfected lysate ( 58.96 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — ALDH6A1
Entrez GeneID
4329GeneBank Accession#
NM_005589.2Protein Accession#
NP_005580.1Gene Name
ALDH6A1
Gene Alias
MGC40271, MMSADHA, MMSDH
Gene Description
aldehyde dehydrogenase 6 family, member A1
Omim ID
603178Gene Ontology
HyperlinkGene Summary
This protein belongs to the aldehyde dehydrogenases family of proteins. This enzyme plays a role in the valine and pyrimidine catabolic pathways. The product of this gene, a mitochondrial methylmalonate semialdehyde dehydrogenase, catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. [provided by RefSeq
Other Designations
aldehyde dehydrogenase 6A1|mitochondrial acylating methylmalonate-semialdehyde dehydrogenase
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Interactome
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Pathway
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Disease
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