MMP8 MaxPab rabbit polyclonal antibody (D01)
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More Files
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human MMP8 protein.
Immunogen
MMP8 (NP_002415.1, 1 a.a. ~ 467 a.a) full-length human protein.
Sequence
MFSLKTLPFLLLLHVQISKAFPVSSKEKNTKTVQDYLEKFYQLPSNQYQSTRKNGTNVIVEKLKEMQRFFGLNVTGKPNEETLDMMKKPRCGVPDSGGFMLTPGNPKWERTNLTYRIRNYTPQLSEAEVERAIKDAFELWSVASPLIFTRISQGEADINIAFYQRDHGDNSPFDGPNGILAHAFQPGQGIGGDAHFDAEETWTNTSANYNLFLVAAHEFGHSLGLAHSSDPGALMYPNYAFRETSNYSLPQDDIDGIQAIYGLSSNPIQPTGPSTPKPCDPSLTFDAITTLRGEILFFKDRYFWRRHPQLQRVEMNFISLFWPSLPTGIQAAYEDFDRDLIFLFKGNQYWALSGYDILQGYPKDISNYGFPSSVQAIDAAVFYRSKTYFFVNDQFWRYDNQRQFMEPGYPKSISGAFPGIESKVDAVFQQEHFFHVFSGPRYYAFDLIAQRVTRVARGNKWLNCRYG
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Mouse (74); Rat (72)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of MMP8 expression in transfected 293T cell line (H00004317-T01) by MMP8 MaxPab polyclonal antibody.
Lane 1: MMP8 transfected lysate(53.40 KDa).
Lane 2: Non-transfected lysate.
Immunoprecipitation
Immunoprecipitation of MMP8 transfected lysate using anti-MMP8 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with MMP8 purified MaxPab mouse polyclonal antibody (B01P) (H00004317-B01P). -
Gene Info — MMP8
Entrez GeneID
4317GeneBank Accession#
NM_002424Protein Accession#
NP_002415.1Gene Name
MMP8
Gene Alias
CLG1, HNC, PMNL-CL
Gene Description
matrix metallopeptidase 8 (neutrophil collagenase)
Omim ID
120355Gene Ontology
HyperlinkGene Summary
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage. Its function is degradation of type I, II and III collagens. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. [provided by RefSeq
Other Designations
PMNL collagenase|matrix metalloproteinase 8|matrix metalloproteinase 8 (neutrophil collagenase)|neutrophil collagenase
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Interactome
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Disease
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