CD46 purified MaxPab rabbit polyclonal antibody (D01P)

Catalog # H00004179-D01P

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Size:100 ug
Price: USD $ 376.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
Images
Western Blot (Transfected lysate)
Application

Western Blot (Transfected lysate)

Western Blot analysis of CD46 expression in transfected 293T cell line (H00004179-T02) by CD46 MaxPab polyclonal antibody.

Lane 1: CD46 transfected lysate(42.70 KDa).
Lane 2: Non-transfected lysate.

  • Specification

    Product Description

    Rabbit polyclonal antibody raised against a full-length human CD46 protein.MaxPab Polyclonal Antibody,MaxPab Polyclonal Antibodies,MaxPab,DNA Immune,DNA Immunization,Immune Technology

    Immunogen

    CD46 (NP_722548.1, 1 a.a. ~ 384 a.a) full-length human protein.

    Sequence

    MEPPGRRECPFPSWRFPGLLLAAMVLLLYSFSDACEEPPTFEAMELIGKPKPYYEIGERVDYKCKKGYFYIPPLATHTICDRNHTWLPVSDDACYRETCPYIRDPLNGQAVPANGTYEFGYQMHFICNEGYYLIGEEILYCELKGSVAIWSGKPPICEKVLCTPPPKIKNGKHTFSEVEVFEYLDAVTYSCDPAPGPDPFSLIGESTIYCGDNSVWSRAAPECKVVKCRFPVVENGKQISGFGKKFYYKATVMFECDKGFYLDGSDTIVCDSNSTWDPPVPKCLKVSTSSTTKSPASSASGPRPTYKPPVSNYPGYPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKKGKADGGAEYATYQTKSTTPAEQRG

    Host

    Rabbit

    Reactivity

    Human

    Quality Control Testing

    Antibody reactive against mammalian transfected lysate.

    Storage Buffer

    In 1x PBS, pH 7.4

    Storage Instruction

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

  • Applications

    Western Blot (Transfected lysate)

    Western Blot analysis of CD46 expression in transfected 293T cell line (H00004179-T02) by CD46 MaxPab polyclonal antibody.

    Lane 1: CD46 transfected lysate(42.70 KDa).
    Lane 2: Non-transfected lysate.
  • Gene Info — CD46

    Entrez GeneID

    4179

    GeneBank Accession#

    NM_153826.2

    Protein Accession#

    NP_722548.1

    Gene Name

    CD46

    Gene Alias

    MCP, MGC26544, MIC10, TLX, TRA2.10

    Gene Description

    CD46 molecule, complement regulatory protein

    Omim ID

    120920 235400

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene is a type I membrane protein and is a regulatory part of the complement system. The encoded protein has cofactor activity for inactivation of complement components C3b and C4b by serum factor I, which protects the host cell from damage by complement. In addition, the encoded protein can act as a receptor for the Edmonston strain of measles virus, human herpesvirus-6, and type IV pili of pathogenic Neisseria. Finally, the protein encoded by this gene may be involved in the fusion of the spermatozoa with the oocyte during fertilization. This gene is found in a cluster on chromosome 1q32 with other genes encoding structural components of the complement system. At least fourteen different transcript variants encoding fourteen different isoforms have been found for this gene. [provided by RefSeq

    Other Designations

    CD46 antigen, complement regulatory protein|OTTHUMP00000034577|OTTHUMP00000034622|OTTHUMP00000034623|OTTHUMP00000034624|OTTHUMP00000034625|OTTHUMP00000034626|OTTHUMP00000034706|antigen identified by monoclonal antibody TRA-2-10|complement membrane cofacto

  • Interactome
  • Pathway
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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