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KCNA1 (Human) Recombinant Protein (Q01)

  • Catalog # : H00003736-Q01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Human KCNA1 partial ORF ( NP_000208.1, 410 a.a. - 495 a.a.) recombinant protein with GST-tag at N-terminal.
  • Sequence:
  • Host:
  • Wheat Germ (in vitro)
  • Theoretical MW (kDa):
  • 35.2
  • Purification:
  • Glutathione Sepharose 4 Fast Flow
  • Quality Control Testing:
  • 12.5% SDS-PAGE Stained with Coomassie Blue.

    QC Testing of H00003736-Q01
  • Storage Buffer:
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Best use within three months from the date of receipt of this protein.
  • Applications
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Application Image
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Gene Information
  • Entrez GeneID:
  • 3736
  • Gene Name:
  • KCNA1
  • Gene Alias:
  • AEMK,EA1,HBK1,HUK1,KV1.1,MBK1,MGC126782,MGC138385,MK1,RBK1
  • Gene Description:
  • potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
  • Gene Summary:
  • This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK). [provided by RefSeq
  • Other Designations:
  • potassium voltage-gated channel subfamily A member 1,voltage-gated potassium channel subunit Kv1.1
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