IL11 monoclonal antibody (M04), clone 3C6
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant IL11.
Immunogen
IL11 (NP_000632, 23 a.a.-199 a.a.) partial recombinant protein.
Sequence
GPPPGPPRVSPDPRAELDSTVLLTRSLLADTRQLAAQLRDKFPADGDHNLDSLPTLAMSAGALGALQLPGVLTRLRADLLSYLRHVQWLRRAGGSSLKTLEPELGTLQARLDRLLRRLQLLMSRLALPQPPPDPPAPPLAPPSSAWGGIRAAHAILGGLHLTLDWAVRGLLLLKTRL
Host
Mouse
Reactivity
Human
Isotype
IgG1
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
ELISA
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Gene Info — IL11
Entrez GeneID
3589GeneBank Accession#
N/AProtein Accession#
-Gene Name
IL11
Gene Alias
AGIF, IL-11
Gene Description
interleukin 11
Omim ID
147681Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. [provided by RefSeq
Other Designations
adipogenesis inhibitory factor|oprelvekin
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Interactome
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Pathway
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Disease
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