IL11 DNAxPab
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human IL11 DNA using DNAx™ Immune technology.
Technology
Immunogen
Full-length human DNA
Sequence
MNCVCRLVLVVLSLWPDTAVAPGPPPGPPRVSPDPRAELDSTVLLTRSLLADTRQLAAQLRDKFPADGDHNLDSLPTLAMSAGALGALQLPGVLTRLRADLLSYLRHVQWLRRAGGSSLKTLEPELGTLQARLDRLLRRLQLLMSRLALPQPPPDPPAPPLAPPSSAWGGIRAAHAILGGLHLTLDWAVRGLLLLKTRL
Host
Rabbit
Reactivity
Human
Purification
Protein A
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Immunofluorescence (Transfected cell)
Flow Cytometry (Transfected cell)
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Gene Info — IL11
Entrez GeneID
3589GeneBank Accession#
NM_000641.2Protein Accession#
NP_000632.1Gene Name
IL11
Gene Alias
AGIF, IL-11
Gene Description
interleukin 11
Omim ID
147681Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the gp130 family of cytokines. These cytokines drive the assembly of multisubunit receptor complexes, all of which contain at least one molecule of the transmembrane signaling receptor IL6ST (gp130). This cytokine is shown to stimulate the T-cell-dependent development of immunoglobulin-producing B cells. It is also found to support the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells. [provided by RefSeq
Other Designations
adipogenesis inhibitory factor|oprelvekin
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Interactome
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Pathway
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Disease
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