IL7R purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Flow Cytometry
FACS analysis of negative control 293 cells (Black) and IL7R expressing 293 cells (Green) using IL7R purified MaxPab mouse polyclonal antibody.
Western Blot (Transfected lysate)
Western Blot analysis of IL7R expression in transfected 293T cell line (H00003575-T01) by IL7R MaxPab polyclonal antibody.
Lane 1: IL7R transfected lysate(50.49 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human IL7R protein.
Immunogen
IL7R (AAH67539.1, 1 a.a. ~ 459 a.a) full-length human protein.
Sequence
MTILGTTFGMVFSLLQVVSGESGYAQNGDLEDAELDDYTFSCYSQLEVNGSQHSLTCAFEDPDVNTTNLEFEICGALVEVKCLNFRKLQEIYFIETKKFLLIGKSNICVKVGEKSLTCKKIDLTTIVKPEAPFDLSVIYREGANDFVVTFNTSHLQKKYVKVLMHDVAYRQEKDENKWTHVNLSSTKLTLLQRKLQPAAMYEIKVRSIPDHYFKGFWSEWSPSYYFRTPEINNSSGEMDPILLTISILSFFSVALLVILACVLWKKRIKPIVWPSLPDHKKTLEHLCKKPRKNLNVSFNPESFLDCQIHRVDDIQARDEVEGFLQDTFPQQLEESEKQRLGGDVQSPNCPSEDVVITPESFGRDSSLTCLAGNVSACDAPILSSSGSLDCRESGKNGPHVYQDLLLSLGTTNSTLPPPFSLQSGILTLNPVAQGQPILTSLGSNQEEAYVTMSSFYQNQ
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Flow Cytometry
FACS analysis of negative control 293 cells (Black) and IL7R expressing 293 cells (Green) using IL7R purified MaxPab mouse polyclonal antibody.Western Blot (Transfected lysate)
Western Blot analysis of IL7R expression in transfected 293T cell line (H00003575-T01) by IL7R MaxPab polyclonal antibody.
Lane 1: IL7R transfected lysate(50.49 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — IL7R
Entrez GeneID
3575GeneBank Accession#
BC067539Protein Accession#
AAH67539.1Gene Name
IL7R
Gene Alias
CD127, CDW127, IL-7R-alpha, IL7RA, ILRA
Gene Description
interleukin 7 receptor
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a receptor for interleukine 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukine 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in the V(D)J recombination during lymphocyte development. This protein is also found to control the accessibility of the TCR gamma locus by STAT5 and histone acetylation. Knockout studies in mice suggested that blocking apoptosis is an essential function of this protein during differentiation and activation of T lymphocytes. The functional defects in this protein may be associated with the pathogenesis of the severe combined immunodeficiency (SCID). [provided by RefSeq
Other Designations
CD127 antigen|interleukin 7 receptor alpha chain
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Interactome
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Pathway
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Disease
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