GZMA monoclonal antibody (M01), clone 4C6
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More Files
- More Functions
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged GZMA is 3 ng/ml as a capture antibody.
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant GZMA.
Immunogen
GZMA (NP_006135.1, 41 a.a. ~ 141 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
PYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITREEPTKQIMLVKKEFPYPCYDPATREGDLKLLQLTEKAKINKYVTILHLPKKGDD
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (69); Rat (68)
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged GZMA is 3 ng/ml as a capture antibody.ELISA
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Gene Info — GZMA
Entrez GeneID
3001GeneBank Accession#
NM_006144Protein Accession#
NP_006135.1Gene Name
GZMA
Gene Alias
CTLA3, HFSP
Gene Description
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
Omim ID
140050Gene Ontology
HyperlinkGene Summary
Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. [provided by RefSeq
Other Designations
CTL tryptase|Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3; Hanukah factor serine protease)|granzyme A
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Interactome
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Pathway
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Disease
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