GZMA polyclonal antibody
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More Files
- More Functions
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human heart tissue using GZMA polyclonal antibody (Cat # PAB17542).
Peptide "+" means "with peptide blocking".
Immunofluorescence
Immunofluorescence analysis of HepG2 cells, using GZMA polyclonal antibody (Cat # PAB17542).
Peptide "+" means "with peptide blocking".
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of GZMA.
Immunogen
A synthetic peptide corresponding to internal of human GZMA.
Host
Rabbit
Reactivity
Human
Specificity
This antibody detects endogenous levels of total GZMA protein.
Form
Liquid
Recommend Usage
Immunohistochemistry (1:50-1:100)
Immunofluorescence (1:500-1:1000)
ELISA (1:5000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (150mM NaCl, 0.02% sodium azide, 50% glycerol)
Storage Instruction
Store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunohistochemistry analysis of paraffin-embedded human heart tissue using GZMA polyclonal antibody (Cat # PAB17542).
Peptide "+" means "with peptide blocking".Immunofluorescence
Immunofluorescence analysis of HepG2 cells, using GZMA polyclonal antibody (Cat # PAB17542).
Peptide "+" means "with peptide blocking".Enzyme-linked Immunoabsorbent Assay
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Gene Info — GZMA
Entrez GeneID
3001Protein Accession#
P12544Gene Name
GZMA
Gene Alias
CTLA3, HFSP
Gene Description
granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
Omim ID
140050Gene Ontology
HyperlinkGene Summary
Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. [provided by RefSeq
Other Designations
CTL tryptase|Granzyme A (Cytotoxic T-lymphocyte-associated serine esterase-3; Hanukah factor serine protease)|granzyme A
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Interactome
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Pathway
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Disease
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