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PDIA3 rabbit monoclonal antibody

  • Catalog # : H00002923-K
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  • Specification
  • Product Description:
  • Rabbit monoclonal antibody raised against a human PDIA3 peptide using ARM Technology.
  • Immunogen:
  • A synthetic peptide of human PDIA3 is used for rabbit immunization.
    Customer or Abnova will decide on the preferred peptide sequence.
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Purification:
  • Protein A
  • Isotype:
  • IgG
  • Quality Control Testing:
  • Antibody reactive against human PDIA3 peptide by ELISA and mammalian transfected lysate by Western Blot.
  • Storage Buffer:
  • In 1x PBS, pH 7.4
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • 1. Customer may provide cell or tissue lysate for antibody screening.
    2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request.
  • Library Construction:
  • Non-fusion antibody library from rabbit spleen (ARM Technology).
  • Expression:
  • Overexpression vector and transfection into 293H cell line.
  • Deliverable:
  • Up to three rabbit IgG clones of 1 mg each will be delivered to customer.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Transfected lysate)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 2923
  • GeneBank Accession#:
  • PDIA3
  • Gene Name:
  • PDIA3
  • Gene Alias:
  • ER60,ERp57,ERp60,ERp61,GRP57,GRP58,HsT17083,P58,PI-PLC
  • Gene Description:
  • protein disulfide isomerase family A, member 3
  • Gene Summary:
  • This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates. [provided by RefSeq
  • Other Designations:
  • 58 kDa microsomal protein,OTTHUMP00000041709,endoplasmic reticulum P58,glucose regulated protein, 58kDa,phospholipase C-alpha,protein disulfide isomerase-associated 3,protein disulfide-isomerase A3
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