GLRA1 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human GLRA1 peptide using ARM Technology.
Immunogen
A synthetic peptide of human GLRA1 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human GLRA1 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — GLRA1
Entrez GeneID
2741GeneBank Accession#
GLRA1Gene Name
GLRA1
Gene Alias
MGC138878, MGC138879, STHE
Gene Description
glycine receptor, alpha 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor. The receptor mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Two transcript variants encoding different isoforms have been found for this gene
Other Designations
OTTHUMP00000160616|glycine receptor, alpha 1 (startle disease/hyperekplexia, stiff man syndrome)|startle disease/hyperekplexia|stiff person syndrome
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