GLRA1 monoclonal antibody (M04), clone 2G4
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant GLRA1.
Immunogen
GLRA1 (NP_000162, 121 a.a. ~ 220 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
IWKPDLFFANEKGAHFHEITTDNKLLRISRNGNVLYSIRITLTLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQEQGAVQVADGLTLPQFILKEE
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.74 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged GLRA1 is approximately 0.1ng/ml as a capture antibody.ELISA
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Gene Info — GLRA1
Entrez GeneID
2741GeneBank Accession#
NM_000171Protein Accession#
NP_000162Gene Name
GLRA1
Gene Alias
MGC138878, MGC138879, STHE
Gene Description
glycine receptor, alpha 1
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a subunit of a pentameric inhibitory glycine receptor. The receptor mediates postsynaptic inhibition in the central nervous system. Defects in this gene are a cause of startle disease (STHE), also known as hereditary hyperekplexia or congenital stiff-person syndrome. Two transcript variants encoding different isoforms have been found for this gene
Other Designations
OTTHUMP00000160616|glycine receptor, alpha 1 (startle disease/hyperekplexia, stiff man syndrome)|startle disease/hyperekplexia|stiff person syndrome
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Interactome
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Pathway
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Disease
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